Table of Contents

Preface. . Part I: What is a virus?:. 1. Towards a Definition of a Virus. 2. Some Methods for Studying Animal Viruses. 3. The Structure of Virus Particles. 4. Classification of Viruses. Part II: Virus Growth in Cells:. 5. The Process of Infection: I. Attachment of Viruses and the Entry of Their Genomes into the Target Cell. 6. The Process of Infection: IIA. The Replication of Viral DNA. 7. The Process of Infection: IIB. Genome Replication in RNA Viruses. 8. The Process of Infection: IIC. The Replication of RNA Viruses with a DNA Intermediate and Vice Versa. 9. The Process of Infection: IIIA. Gene Expression in DNA Viruses and Reverse-Transcribing Viruses. 10. The Process of Infection: IIIB. Gene Expression and its Regulation in RNA Viruses. 11. The Process of Infection: IV. The Assembly of Viruses. Part III: Virus Interactions with the Whole Organism:. 12. The Immune System and Virus Neutralization. 13. Interactions Between Animal Viruses and Cells. 14. Animal Virus-Host Interactions. 15. Mechanisms in Virus Latency. 16. Transmission of Viruses. 17. The Evolution of Viruses. Part IV: Viruses and Disease:. 18. Human Viral Disease: An Overview. 19. HIV & AIDS. 20. Carcinogenesis and Tumor Viruses. 21. Vaccines and Antivirals: The Prevention and Treatment of Virus Diseases. 22. Prion Diseases. 23. Horizons in Human Virology. Appendixes: Survey of Virus Properties. Index

About the Author

Nigel Dimmock is an internationally acclaimed virologist who has spent the major part of his career at the University of Warwick's Department of Biological Sciences, where he is currently an emeritus professor. His main research interests are influenza viruses, HIV, and antiviral immunology. Andrew Easton is professor of virology at the University of Warwick. Having spent two years working in the pharmaceutical industry he joined the department at Warwick in 1983 and became Head of the Virology Group in 1998. Easton's research focuses on the molecular biology of pneumoviruses. Keith Leppard is a reader at the University of Warwick. His research focuses on the interactions of adenovirus with the host cell, in particular the effects of adenoviral proteins on functions of the cell nucleus, and on the development of adenovirus as a gene delivery vehicle.