Table of Contents

I. Introduction to physiology: the cell and general physiology 1. Functional organization of the human body and control of the 'internal environment 2. The cell and its functions 3. Genetic control of protein synthesis, cell function, and cell reproduction II. Membrane physiology, nerve, and muscle 4. The DNA code in the cell nucleus is transferred to an RNA code in the cell cytoplasm -- the process of transcription 5. Membrane potentials and action potentials 6. Contraction of skeletal muscle 7. Excitation of skeletal muscle: neuromuscular transmission and excitation-contraction coupling 8. Contraction and excitation of smooth muscle III The heart 9. Cardiac muscle: the heart as a pump and function of the heart muscles 10. Rhythmical excitatory and conductive system of the heart 11. The normal electrocardiogram 12. Electrocardiographic interpretation of cardicac muscle and coronary blood flow abnormalities: ventricle analysis 13.Cardiac arrhythmias and their electrocardiographic interpretation IV. The circulation 14. Overview of the circulation; medical biophysics of pressure, flow, and resistance 15. Vascular distensibility and functions of the arterial and venous systems 16. The microcirculation and lymphatic system: capillary fluid exchange, interstitial fluid, and lymph flow 17. Local and humoral control of tissue flow by the tissues 18. Nervous regulation of the circulation, and rapid control of arterial pressure 19. Role of the kidneys in long-term control of arterial pressure and in hypertension: the integrated system for aterial pressure regulation 20. Cardiac output, venous return, and their regulation 21. Muscle blood flow and cardiac output during exercise; the coronary circulation and ischemic heart disease 22. Cardiac failure 23. Heart valves and heart sounds; dynamics of valvular and congenital heart defects 24. Circulatory shock and physiology of its treatment V. The body fluids and kidneys 25. The body fluids compartments: extracellular and intracellular fluids; intersitial fluid and edema 26. Urine formation by the kidneys: I. Glomerular filtration, renal blood flow, and their control 27. Urine formation by the kidneys: II. Tubular reabsorption and secretion 28. Urine concentration and dilution; regulation of extracellular fluid osmolarity and sodium concentration 29. Renal regulation of potassium, calcium, phosphate, and magnesium; integration of renal mechanisms for control of blood volume and extracellular fluid volume 30. Acid-base regulation 31. Diuretics and kidney diseases VI. Blood cells, immunity, and blood coagulation 32. Red blood cells, anemia, and polycythemia 33. Resistance of the body to infection: I. Leukocytes, granulocytes, the monocyte-macrophage system, and inflammation 34. Resistance of the body to infection: II. Immunity and allergy 35. Blood types; transfusion; tissue and organ transplantation 36. Hemostasis and blood coagulation VII. Respiration 37. Pulmonary ventilation 38. Pulmonary circulation, pulmonary edema, pleural fluid 39. Physical principles of gas exchange; diffusion of oxygen and carbon dioxide through the respiratory membrane 40. Transport of oxygen and carbon dioxide in blood and tissue fluids 41. Regulation of respiration 42. Respiratory insufficiency - pathophysiology, diagnosis, oxygen therapy VIII. Aviation, space, and deep-sea diving physiology 43. Aviation, high-altitude, and space physiology 44. Physiology of deep-sea diving and other hyperbaric conditions IV. The nervous system: A. General principles and sensory physiology 45. Organization of the nervous system, basic functions of synapses, "Transmitter substances" 46. Sensory receptors, neuronal circuits for processing information 47. Somatic sensations: I. General organization, the tactile and position senses 48. Somatic sensations: II. Pain, headache, and thermal sensations X. The nervous system: B. The special senses 49. The eye: I. Optics of vision 50. The eye: II. Receptor and neural function of the retina 51. The eye: III. Central neurophysiology of vision 52. The sense of hearing 53. The chemical senses - taste and smell XI. The nervous system: C. Motor and integrative neurophysiology 54. Motor functions of the spinal cord; the cord reflexes 55. Cortical and brain stem control of motor function 56. Contributions of the cerebellum and basal ganglia to overall motor control 57. Cerebral cortex, intellectual functions of the brain, learning and memory 58. Behavioral and motivational mechanisms of the brain - the limbic system and the hypothalamus 59. States of brain activity - sleep, brain waves, epilepsy, psychoses 60. The autonomic nervous system and the adrenal medulla 61. Cerebral blood flow, cerebrospinal fluid, and brain metabolism XII. Gastrointestinal physiology 62. General principles of gastrointestinal function - motility, nervous control, and blood circulation 63. Propulsion and mixing of food in the alimentary canal 64. Secretory functions of the alimentary tract 65. Digestion and absorption in the gastrointestinal tract 66. Physiology of gastrointestinal disorders XIII. Metabolism and temperature regulation 67. Metabolism of carbohydrates 68. Lipid metabolism 69. Protein metabolism 70. The liver 71. Dietary balances; regulation of feeding; obesity and starvation; vitamins and minerals 72. Energetics and metabolic rate 73. Body temperature, temperature regulation, and fever XIV. Endocrinology and reproduction 74. Introduction to endocrinology 75. Pituitary hormones and their control by the hypopthalamus 76. Thyroid metabolic hormones 77. Adenocortical hormones 78. Insulin, glucagon, and diabetes mellitus 79. Parathyroid hormone, calcitonin, calcium and phosphate metabolism, vitamin D, bone, and teeth 80. Reproductive and hormonal functions of the mail (and function of the pineal gland) 81. Female physiology before pregnancy and female hormones 82. Pregnancy and lactation 83. Fetal and neonatal physiology XV. Sports physiology 84. Sports physiology

About the Author

John E. Hall, Ph.D. Arthur C. Guyton Professor and Chair Department of Physiology & Biophysics Associate Vice Chancellor for Research University of Mississippi Medical Center Jackson, MS 39216-4505 601-984-1801 jehall@umc.edu