An enlightening and passionately written work, Generic opens the 'black box' of the pharmaceutical world. This book will deeply impact the way we imagine and practice medicine in the future. -- Siddhartha Mukherjee, Assistant Professor of Medicine, Columbia University, author of The Emperor of All Maladies: A Biography of Cancer An extraordinarily timely and important contribution to our understanding of health practice and public policy. The status of generics is a significant subject in itself, and also a tool to think with, linking physiology and policy, business history and clinical options. Generic is a book that should be read by anyone with a serious interest in contemporary health care. -- Charles E. Rosenberg, Professor of the History of Science and the Ernest E. Monrad Professor in the Social Sciences, Harvard University Jeremy Greene brings his knowledge and wisdom as both historian and physician to bear on the economics and politics of branding, marketing, and consumerism in health care. Most intriguingly, he asks fundamental questions about what it means to say one drug is the same as another. Fascinating and eye-opening. -- Susan Strasser, Richards Professor of American History, University of Delaware, author of Satisfaction Guaranteed: The Making of the American Mass Market Generic is a gem. Original, multi-layered, and powerfully narrated, the book unearths the history and value of generic drugs. While illuminating the dynamic interface of medicine, public health, and the marketplace in the US and beyond, Greene has crafted a vital compass that can greatly help us to understand and navigate the pharmaceutical present. -- Joao Biehl, Susan Dod Brown Professor of Anthropology, Princeton University, author of Will to Live: AIDS Therapies and the Politics of Survival The story of generic drugs is rife with intrigue, deceit, complex scientific debate, legislative wrangling, backstabbing, internecine warfare among health professions and government regulators, under-the-table deals worth billions of dollars, headline-grabbing prison sentences for trusted officials, and power struggles among monied interest groups. But Jeremy A. Greene's Generic is not just a lurid story: it is also rich with lessons in the negotiating of health policy, the brokering of legitimate scientific disputes to craft the best possible regulatory decisions for the public health, the struggles to make health care more affordable for as many citizens as possible, and the transformation of the global pharmaceutical marketplace. A provocative, thoughtful, and comprehensive look into an industry that took on big pharma and organized medicine. -- John P. Swann, author of Academic Scientists and the Pharmaceutical Industry: Cooperative Research in Twentieth-Century America
Preface to the 2016 Edition
Acknowledgments
Introduction. The Same but Not the Same
Part I. What's in a Name?
Chapter 1. Ordering the World of Cures
Chapter 2. The Generic as Critique of the Brand
Part II. No Such Thing as a Generic Drug?
Chapter 3. Drugs Anonymous
Chapter 4. Origins of a Self- Effacing Industry
Chapter 5. Generic Specificity
Part III. The Sciences of Similarity
Chapter 6. Contests of Equivalence
Chapter 7. The Significance of Differences
Part IV. Laws of Substitution
Chapter 8. Substitution as Vice and Virtue
Chapter 9. Universal Exchange
Part V. Paradoxes of Generic Consumption
Chapter 10. Liberating the Captive Consumer
Chapter 11. Generic Consumption in the Clinic, Pharmacy, and
Supermarket
Part VI. The Generic Alternative
Chapter 12. Science and Politics of the "Me- Too" Drug
Chapter 13. Preferred Drugs, Public and Private
Chapter 14. The Global Generic
Conclusion. The Crisis of Similarity
List of Abbreviations
Notes
Index
Jeremy A. Greene, M.D., Ph.D., is associate professor of medicine and the history of medicine and the Elizabeth Treide and A. McGehee Harvey Chair in the History of Medicine at the Johns Hopkins University School of Medicine. He is the author of Prescribing by Numbers: Drugs and the Definition of Disease and coeditor of Prescribed: Writing, Filling, Using, and Abusing the Prescription in Modern America, both published by Johns Hopkins.
Greene turns the concept of generic as 'ho-hum' on its head with this jam-packed survey of the effects culture, medicine, and politics have exerted on today's ubiquitous generic drugs for the last 50 years. Publishers Weekly Greene's brilliant book is the first full-length monograph to trace the history of how Americans think about generics, and it is going to be the key reference for many years to come. -- Stefan Ecks Somatosphere Jeremy Greene's Generic: The Unbranding of Modern Medicine fascinates because the very meaning of the key term "generic" is so unstable. Every time the reader thinks they have a handle on its dimensions, another four open up. -- Joseph Dumit Somatosphere Greene's book is a dizzying historical-political-social-cultural account of the forms generic drugs have taken over past several decades. -- Todd Meyers Somatosphere This is an excellent and recommended history of how the generic drug market came to be. Library Journal Fascinating and thought-provoking. -- Stephen Goddard History Wire - Where the Past Comes Alive Dr. Greene's gripping and eye-opening accounts of the scientific, social, and political debates that happened along the way keep the reader hooked and engaged... [He] is both scholar and storyteller, interspersing fascinating historical narratives with complex scientific discussion. -- Miriam Reisman P&T Community Greene should be congratulated for bringing this subject to life-with a mix of anecdote, scholarship, and elegant prose. Lancet As Jeremy Greene lays out in his excellent book, the story of the generic drug industry is is far more complicated-and far more interesting than most of us might guess... [Greene] provides readers with a useful framework for understanding how we got to where we are and how we might apply the lessons of the past to the challenges we face today. -- Elizabeth Richardson Health Affairs Generic: The Unbranding of Modern Medicine comes from a physician and historian who offers a history of not just the development of generic drugs, but how they differ from the original. Within his examination are important insights on how drugs are made, what parts of a pill really matter, issues of therapeutic similarity and difference, and more. It's a wide-ranging history that embraces ethical, scientific, health, and economic issues and it provides insights on the history of generic drugs in America and the problems associated with scientific and medical changes in the public eye. The result is a survey that belongs in any health collection and many a general-interest holding. The Midwest Book Review This fine, stimulating, and entertaining book offers much food for thought. -- Nicolas Rasmussen Journal of the History of Medicine and Allied Sciences Well written and informative... bring[s] to life a tangled web of competing interests. -- Phillip Broadwith Chemistry World A theoretical and empirical primer that explains the success and failure of generics and what it means to choose between generic and brand name drugs. Extensively researched and documented, Generic is the first book to chronicle the development of generics, and will probably be the key reference on the topic for some time... A book that should be read by anybody with a serious interest in contemporary healthcare. -- Debra Swoboda Sociology of Health and Illness The generic drug industry... has been glorified as the antidote to exorbitant drug prices, and vilified as the purveyor of poisonous (or at least less effective) counterfeit drugs. Yet in Generic, Jeremy Greene has a far more nuanced, and far more interested, tale to tell... Greene's vitally important book... explicitly asks us to consider how much the tensions concerning times and places examined in the book are the same as those we face today... or at least similar enough in ways that we should find relevant. The answer is, very much. -- Scott H. Podolsky Studies in the History and Philosophy of Science Physician/historian Greene provides a thoroughly researched discussion about generic products derived from innovative or brand-name drugs, focusing on their "social, political, and cultural history"... Greene ably argues for generic by providing inside details about the drug approval process. Choice
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