List of contributors, viii
Preface to the third edition, xiv
Classification of recommendations and levels of evidence, xvi
List of abbreviations, xvii
Part I: General concepts and critical appraisal
Salim
Yusuf, Editor
1 Evidence-based decision making: patient–physician interface,
3
Philip J Devereaux, Marc Pfeffer, Salim Yusuf
2 Obtaining incremental information from diagnostic tests,
14
Raymond J Gibbons
3 Clinical trials and meta-analysis, 26
Jonathan R Emberson, Colin Baigent
4 Understanding concepts related to health economics, 38
Mark A Hlatky
5 Major vascular complications in patients undergoing
non-cardiac surgery: magnitude of the problem, risk prediction,
surveillance, and prevention, 47
Philip J Devereaux, Matthew Chan, John Eikelboom
6 Implementing evidence-based medicine in cardiology, 63
Brahmajee K Nallamothu, Thomas T Tsai, Jack V Tu
7 The application of evidence-based medicine to employment
fitness standards: the transportation industries with special
reference to aviation, 79
Michael Joy
Part II: Prevention of cardiovascular diseases
Salim
Yusuf and John A Cairns, Editors
8 Global perspective on cardiovascular disease, 95
K Srinath Reddy
9 Avoidance of worldwide vascular deaths and total deaths from
smoking, 111
Prabhat Jha, Prem Mony, James Moore, Witold Zatonski
10 Tobacco and cardiovascular disease: achieving smoking
cessation in cardiac patients, 125
Andrew Pipe
11 Lipids and cardiovascular disease, 138
Malcolm Law
12 Use of lipid-lowering agents in the prevention of
cardiovascular disease, 147
R Alan Failor, Jeffrey L Probstfi eld
13 Blood pressure and cardiovascular disease, 165
Curt D Furberg, Bruce M Psaty, Elsayed Z Soliman
14 Dysglycemia and the risk of cardiovascular events, 179
Hertzel C Gerstein, Zubin Punthakee
15 Physical activity and exercise in cardiovascular disease
prevention and rehabilitation, 190
Ray W Squires
16 Psychosocial factors, 201
Annika Rosengren
17 The social determinants of cardiovascular disease, 211
Martin McKee, Clara K Chow
18 Obesity, 221
Raj S Padwal, Arya M Sharma
19 Ethnicity and cardiovascular disease, 235
Clara K Chow, Sonia S Anand, Salim Yusuf
20 Fetal origins of coronary artery disease, 258
Katherine M Morrison, Stephanie Atkinson, Koon K Teo
21 Genetics of coronary heart disease, 268
Michael S Cunnington, Bernard D Keavney
22 Molecular genetics of cardiovascular disorders, 288
Ali J Marian, Robert Roberts
23 Diet and cardiovascular disease, 304
K Srinath Reddy
24 Integrating approaches to prevention of cardiovascular
disease, 328
David A Wood, Kornelia Kotseva
Part IIIa: Stable coronary artery disease
John A
Cairns and Bernard J Gersh, Editors
25 Medical management of stable coronary artery disease, 345
William E Boden
26 Percutaneous intervention, 357
David A Wood, Rohit Khurana, Christopher E Buller
27 Surgical coronary artery revascularization, 379
Morgan L Brown, Thoralf M Sundt III
28 Comparisons of percutaneous coronary intervention and
coronary artery bypass grafting, 392
Arashk Motiei, Thoralf M Sundt III, Charanjit S Rihal
Part IIIb: Acute coronary syndromes
John A Cairns and
Bernard J Gersh, Editors
29 Non-ST segment elevation acute coronary syndromes: unstable
angina and non-ST segment elevation myocardial infarction, 409
Pierre Theroux, John A Cairns
30 Early prehospital management of ST segment elevation
myocardial infarction, 444
Robert C Welsh, Paul W Armstrong
31 Reperfusion therapies for ST segment elevation myocardial
infarction, 456
Joseph B Muhlestein, Jeffrey L Anderson
32 Antithrombotic therapies for patients with ST segment
elevation myocardial infarction, 475
Andrew J Lucking, Keith A A Fox
33 Complications after myocardial infarction, 495
Peter L Thompson
34 An integrated approach to the management of patients after
the early phase of ST segment elevation myocardial infarction,
516
Pedro L Sánchez, Francisco Fernández- Avilés
Part IIIc: Arrhythmias
A John Camm and John A Cairns,
Editors
35 Atrial fibrillation: rhythm and rate control therapies,
531
Irina Savelieva, Albert L Waldo, A John Camm
36 Atrial fi brillation: upstream therapies, 568
Antonios Kourliouros, Irina Savelieva, Marjan Jahangiri, A John
Camm
37 Atrial fibrillation: antithrombotic therapy, 581
John A Cairns, Stuart Connolly
38 Ablation therapy for atrial fi brillation, 596
Conor D Barrett, Chi Keong Ching, Luigi Di Biase, Claude S Elayi,
David J Burkhardt, Rodney Horton, Andrea Natale
39 Supraventricular tachycardia, 606
Erica D Penny-Peterson, Gerald V Naccarelli
40 Prevention and treatment of life-threatening ventricular
arrhythmia and sudden death, 619
Carlos A Morillo, Adrian Baranchuk
41 Pacemaker therapy, including cardiac resynchronization
therapy, 636
William D Toff, A John Camm
42 Syncope, 673
David G Benditt, Fei Lu, Scott Sakaguchi
43 Cardiopulmonary resuscitation, 692
Michael Colquhoun
44 Arrhythmias due to monogenic disorders, 706
Dawood Darbar, Prince Kannankeril, Dan M L Roden
45 Arrhythmiagenic right ventricular cardiomyopathy, 721
Deirdre Ward, Perry M Elliott
Part IIId: Specifi c cardiovascular disorders: left
ventricular dysfunction
Salim Yusuf, Editor
46 Epidemiology and prevention of heart failure and management
of asymptomatic left ventricular systolic dysfunction, 735
J Paul Rocchiccioli, John J V McMurray
47 Management of overt heart failure, 756
Paul J Hauptman, Karl Swedberg
48 Acute myocarditis and dilated cardiomyopathy, 784
Leslie T Cooper Jr, Oyere K Onuma
49 Management of hypertrophic cardiomyopathy, 796
Barry J Maron
50 Infective and infi ltrative cardiomyopathies, 808
Stavros Kounas, Perry M Elliott
51 Chagas’ heart disease, 823
J Antonio Marin-Neto, Anis Rassi Jr, Benedito Carlos Maciel, Marcus
Vinicius Simões, André Schmidt
Part IIIe: Specifi c cardiovascular disorders: pericardial
disease
Bernard J Gersh, Editor
52 Pericardial disease: an evidence-based approach to clinical
management, 845
Faisal F Syed, Bongani M Mayosi
Part IIIf: Specifi c cardiovascular disorders: valvular heart
disease
Bernard J Gersh, Editor
53 Rheumatic heart disease: prevention and acute treatment,
861
Bongani M Mayosi, Patrick J Commerford
54 Mitral valve disease: indications for surgery, 869
Blase A Carabello
55 Surgical indications in aortic valve disease, 878
Sunil Mankad, Heidi M Connolly, Shahbudin H Rahimtoola
56 Non-surgical aortic valve therapy: balloon valvuloplasty and
transcatheter aortic valve replacement, 896
Robert H Boone, John G Webb
57 Balloon valvuloplasty: mitral valve, 913
Zoltan G Turi
58 Valve repair and choice of valve, 927
Shafie S Fazel, Tirone E David
59 Infective endocarditis, 941
Zainab Samad, Andrew Wang
60 Antithrombotic therapy after heart valve replacement, 957
Jack C J Sun, John W Eikelboom
Part IIIg: Specifi c cardiovascular disorders: other
conditions
Bernard J Gersh and Salim Yusuf, Editors
61 Stroke, 971
Brian H Buck, Ashfaq Shuaib, Craig Anderson
62 Heart disease and pregnancy, 993
Rachel M Wald, Samuel C Siu
63 Adult congenital heart disease, 1006
Elisabeth Bédard, Michael A Gatzoulis
64 Venous thromboembolic disease, 1032
Lori-Ann Linkins, Clive Kearon
65 Peripheral arterial disease, 1050
Catherine McGorrian, Sonia S Anand
66 Cardiac risk in those undergoing non-cardiac surgery,
1068
Ameeth Vedre, Kim A Eagle
67 Clinical management of diseases of the aorta, 1079
Thoralf M Sundt III
68 Cardiac transplantation: indications and postoperative
management, 1099
Barry Boilson, Sudhir Kushwaha
69 Renal dysfunction, 1110
Johannes F E Mann, Ernesto L Schiffrin
70 Pulmonary hypertension, 1118
Brendan P Madden
Part IV: Clinical applications
Ernest L Fallen,
Editor
71 Clinical applications of external evidence, 1135
Ernest L Fallen, Salim Yusuf
72 Stable angina: choice of PCI versus CABG versus drugs,
1138
William S Weintraub
73 Non-ST segment acute coronary syndrome, 1142
David Fitchett
74 Acute ST segment elevation myocardial infarction, 1152
Ernest L Fallen
75 Secondary prevention strategies post myocardial infarction,
1157
Jacques Genest
76 Heart failure, 1164
Michael M Givertz, Garrick C Stewart
77 Atrial fibrillation, 1170
Michael Klein
78 The case for and against implantable cardioverter
defibrillators in patients with coronary artery disease, 1174
Jeffrey S Healey
79 Bradyarrhythmias – choice of pacemakers, 1178
Pablo B Nery, Carlos A Morillo
80 Peripheral arterial disease with suspect coronary artery
disease, 1183
Victor Aboyans, Michael H Criqui
81 Valvular heart disease: timing of surgery, 1187
Jon-David R Schwalm, Victor Chu
Index, 1191
The colour plate section can be found facing p. 941
Salim Yusuf, Professor of Medicine, Heart and Stroke
Foundation Chair in Cardiology, and Director of the Population
Health Research Institute, McMaster University, Hamilton,
Ontario.
John Cairns Dean, Faculty of Medicine, University of
British Columbia.
John Camm, Professor of Clinical Cardiology and Head of
the Department of Cardiac & Vascular Sciences at St George's,
University of London.
Ernest Fallen, Professor Emeritus in Cardiology and Tutor
in Cardiology Residency Program, McMaster University, Hamilton,
Ontario.
Bernard Gersh, Professor of Medicine, Department of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.
"Edited by a cadre of highly respected clinical researchers and
academicians, the third edition will be a welcome addition to the
shelves of cardiologists or primary care physicians with an
interest in the dynamic field of cardiology." (JAMA, August 11,
2010)
"The text is recommended as a reference text for cardiac centres,
cardiologists, cardiac nurse specialists and academic and research
institutions." (Nursing Standard, April 2010) "The is a useful
addition to the field of cardiology that expands on current
comprehensive books ... .The authors have succeeded in creating a
multidimensional reference that fulfills their objectives,
explaining the how and why of specific interventions." (Doody's,
April 2010)
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