Table of Contents

��������� Section 1: Structure and Function of the Kidneys and Their Clinical Assessment



Overview of Kidney Function and Structure
Kidney Development
Assessment of Glomerular Filtration Rate in Acute and Chronic Settings
Urinalysis and Urine Microscopy
Hematuria and Proteinuria
Kidney Imaging
Section 2: Acid-Base, Fluid, and Electrolyte Disorders

Hyponatremia and Hypoosmolar Disorders
Hypernatremia
Edema and the Clinical Use of Diuretics
Disorders of Potassium Metabolism
Disorders of Mineral Metabolism: Calcium, Phosphorus, and Magnesium
Approach to Acid-Base Disorders
Metabolic Acidosis
Metabolic Alkalosis
Respiratory Acidosis and Alkalosis
Section 3: Glomerular Diseases

Glomerular Clinicopathologic Syndromes
Minimal Change Disease
Focal Segmental Glomerulosclerosis
Membranous Nephropathy
Immunoglobulin A Nephropathy and Related Disorders
Goodpasture Syndrome and Other Antiglomerular Basement Membrane Diseases
Section 4: The Kidney in Systemic Disease

Postinfectious Glomerulonephritis
Kidney Involvement in Systemic Vasculitis
Kidney Manifestations of Systemic Lupus Erythematosus
Pathogenesis, Pathophysiology and Treatment of Diabetic Nephropathy
Dysproteinemias and Amyloidosis
Thrombotic Microangiopathies
Viral Nephropathies: Human Immunodeficiency Virus, Hepatitis C Virus, and Hepatitis B Virus
Acute Cardiorenal Syndrome
Hepatorenal Syndrome and Other Liver-Related Kidney Diseases
The Kidney in Cancers
Section 5: Acute Kidney Injury

Pathophysiology of Acute Kidney Injury
Clinical Approach to the Diagnosis of Acute Kidney Injury
Acute Tubular Injury and Acute Tubular Necrosis
Acute Interstitial Nephritis
Management of Acute Kidney Injury
Section 6: Drugs and the Kidney

Kidney Disease Caused by Therapeutic Agents
Principles of Drug Therapy in Patients with Reduced Kidney Function
Section 7: Hereditary Kidney Disorders

Genetically Based Renal Transport Disorders
Sickle Cell Nephropathy
Polycystic and Other Cystic Kidney Diseases
Nephronophthisis and Medullary Cystic Kidney Disease
Alport Syndrome and Related Disorders
Fabry Disease
Section 8: Tubulointerstitial Nephropathies and Disorders of the Urinary Tract

Chronic Tubulointerstitial Disease
Obstructive Uropathy
Nephrolithiasis
Urinary Tract Infection & Pyelonephritis
Section 9: The Kidney in Special Circumstances

The Kidney in Infants and Children
The Kidney in Pregnancy
Kidney Disease in the Elderly
Section 10: Chronic Kidney Disease and Its Therapy

Pathophysiology of Chronic Kidney Disease
Staging and Management of Chronic Kidney Disease
Nutrition and Kidney Disease
Bone Disorders in Chronic Kidney Disease
Cardiac Function and Cardiovascular Disease in Chronic Kidney Disease
Anemia and Other Hematologic Complications of Chronic Kidney Disease
Section 11: Kidney Replacement Therapies: Dialysis and Transplantation

Hemodialysis
Peritoneal Dialysis
Outcomes of Kidney Replacement Therapies
Selection of Prospective Kidney Transplant Recipients and Donors
Posttransplantation Monitoring and Outcomes
Immunosuppression in Transplantation
Infectious Complications of Kidney Transplantation
Section 12: Hypertension

Pathogenesis of Hypertension
Evaluation and Management of Hypertension
Secondary Hypertension

About the Author

Associate Professor of Medicine, Tufts University School of Medicine, Division of Nephrology, Tufts Medical Center, Boston, Massachusetts

Reviews

"This is a very useful resource for the nephrology community. The field is quickly changing and potentially complex, but this book uses simple language and dynamic images to create an excellent teaching tool. There are few resources that include all relevant information in one place, but despite the growth of chronic kidney disease, this update does a good job of incorporating the important changes in the field. The online features on the associated website also enhance the value of the book. I plan to encourage nephrology trainees to use this resource for their education."-Jon Webb, MD(University of Kentucky College of Medicine) Doody Review: 83/100