Table of Contents

Preface; Cancer and Aging as Consequences of Un-Repaired DNA Damage; Radiation-Induced DNA Damage Responses as Novel Targets in Cancer Treatments; BRIT1, A Novel DNA Damage Responsive Protein Dysfunctioned in Primary Microcephaly and Cancer; Polymorphisms in Genes Involved in DNA-Damage Processing and Their Effect on Cancer Risk; HTLV-I Tax Promotes Genomic Instability by Interfering with Repair of DNA Breaks; Genotoxicity and Biomonitoring: Micronuclei in Peripheral Blood and Epithelial Cells; Assays for the Quantitative Characterization of Genomic, Mitochondrial and Plasmid DNA; DNA Damage through Photo-Induced Electron Transfer and Photosensitized Generation of Reactive Oxygen Species; Consecutive Adenine Sequences Serve as Potential Targets in Photosensitized Oxidative DNA Damage; A Novel Methodology to Characterize DNA Damage Utilizing Phosphodiesterase I Function; Factors Governing the Recurrence and Breakpoint Distribution of Chromosomal Translocations in Human Tumors; Current Knowledge on Lead as an Inducer of Human DNA Damage; DNA Damage Signaling in Human Skin Cells Exposed to Hexavalent Chromium; Comparison of DNA Damage and the Expression of Repair Related Molecules, Including DNA Polymerase-ss, APE/ref-1, PCNA, and GADD45, in Human T and B Lymphocytes Exposed to Hydrogen Peroxide and Methyl Methanesulfonate; Mutational Hotspots of TP53 Gene Associated to DNA Damage; Mutation Detection in the TP53 Gene: Alternatives in Point Mutation Technologies; Index.