Table of Contents

Management of Information in Distributed Biomedical Collaboratories.- Enabling Public Data Sharing: Encouraging Scientific Discovery and Education.- Mediator Infrastructure for Information Integration and Semantic Data Integration Environment for Biomedical Research.- System Biology of Gene Regulation.- Current Computational Methods for Prioritizing Candidate Regulatory Polymorphisms.- Methods of Information Geometry in Computational System Biology (Consistency between Chemical and Biological Evolution).- Protein Structure Prediction Based on Sequence Similarity.- Applications of Bioinformatics to Protein Structures: How Protein Structure and Bioinformatics Overlap.- Knowledge Discovery via Machine Learning for Neurodegenerative Disease Researchers.- Brain Model of Text Animation as a Data Mining Strategy.- Processes Parallel Execution Using Grid Wizard Enterprise.- Single Sign-On in a Grid Portal.

Reviews

From the reviews: “Technicians and researchers from San Diego, California survey novel cyber-infrastructures that are currently under development in various biomedical centers around the world. They describe several architectures for large-scale collaboration across multiple centers, modern approaches in various areas of bioinformatics, and software challenges and strategies for overcoming them. … The material could be helpful to practitioners working in bioinformatics or students preparing for it.” (SciTech Book News, March, 2010) “This volume in the Methods in Molecular Biology series provides an overview of novel cyberinfrastructures that are fundamental to present-day biomedical informatics. … Scientists involved in biomedical informatics … who are active in the field of biomedical research are the intended audience. This includes both first-time and seasoned students and biomedical researchers who are interested in using informatics technologies in their laboratories. … This is an excellent contribution to the literature dedicated to the study of bioinformatics in biomedical sciences.” (Ruben Mestril, Doody’s Review Service, February, 2010)